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Xiao-Dong Cong Selected Research

argirein

1/2018Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats.
1/2018Improvement of vascular dysfunction by argirein through inhibiting endothelial cell apoptosis associated with ET-1/Nox4 signal pathway in diabetic rats.
9/2013Hypoxia alters pharmacokinetics of argirein because of mitochondrial dysfunction that is alleviated by apocynin.
8/2013Male hypogonadism induced by high fat diet and low dose streptozotocin is mediated by activated endoplasmic reticulum stress and IκBβ and attenuated by argirein and valsartan.
6/2013Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver.
1/2013Argirein alleviates corpus cavernosum dysfunction by suppressing pro-inflammatory factors p66Shc and ER stress chaperone Bip in diabetic rats.
8/2012Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein.
6/2012ER stress, p66shc, and p-Akt/Akt mediate adjuvant-induced inflammation, which is blunted by argirein, a supermolecule and rhein in rats.

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Xiao-Dong Cong Research Topics

Disease

4Inflammation (Inflammations)
04/2014 - 06/2012
2Tonsillitis
12/2018 - 04/2017
2Insulin Resistance
01/2018 - 06/2013
2Edema (Dropsy)
08/2012 - 06/2012
1Lymphoma (Lymphomas)
01/2018
1Heart Failure
01/2018
1B-Cell Leukemia (Leukemia, B Cell)
01/2018
1Mitochondrial Diseases (Mitochondrial Disease)
09/2013
1Hypoxia (Hypoxemia)
09/2013
1Hypogonadism (Hypergonadotropic Hypogonadism)
08/2013
1Leukemia
06/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
06/2013
1Erectile Dysfunction
01/2013

Drug/Important Bio-Agent (IBA)

8argireinIBA
01/2018 - 06/2012
5rheinIBA
01/2018 - 06/2012
4NADPH Oxidases (NAD(P)H oxidase)IBA
01/2018 - 06/2012
3Proteins (Proteins, Gene)FDA Link
01/2018 - 06/2012
3Arginine (L-Arginine)FDA Link
01/2018 - 08/2012
2Anti-Bacterial Agents (Antibiotics)IBA
12/2018 - 04/2017
2Glucose (Dextrose)FDA LinkGeneric
01/2018 - 06/2013
2acetovanillone (apocynin)IBA
04/2014 - 09/2013
2Carrier Proteins (Binding Protein)IBA
06/2013 - 01/2013
1Nonesterified Fatty Acids (NEFA)IBA
01/2018
1Palmitic Acid (Hexadecanoic Acid)IBA
01/2018
1Caspase 3 (Caspase-3)IBA
01/2018
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
01/2018
1AcidsIBA
04/2014
1TriterpenesIBA
04/2014
1Isoproterenol (Isoprenaline)FDA LinkGeneric
04/2014
1NADP (NADPH)IBA
09/2013
1Apolipoproteins AIBA
09/2013
1Oxidoreductases (Dehydrogenase)IBA
09/2013
1Valsartan (Vals)FDA Link
08/2013
1Streptozocin (Streptozotocin)FDA Link
08/2013
1Insulin Receptor Substrate ProteinsIBA
06/2013
1Endoplasmic Reticulum Chaperone BiPIBA
06/2013
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
06/2013
1CarbohydratesIBA
06/2013
1DNA (Deoxyribonucleic Acid)IBA
06/2013
1Insulin (Novolin)FDA Link
06/2013
1LipidsIBA
06/2013
1Phosphotransferases (Kinase)IBA
06/2013
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
06/2013
1Transcription Factor CHOPIBA
06/2013
1Leptin ReceptorsIBA
06/2013
1Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
01/2013
1Nitric Oxide Synthase (NO Synthase)IBA
01/2013
1Aquaporin 4IBA
08/2012
1Indomethacin (Indometacin)FDA LinkGeneric
08/2012
1Transcription Factors (Transcription Factor)IBA
08/2012
1CarrageenanIBA
08/2012
1CytokinesIBA
06/2012
1Ibuprofen (Motrin)FDA LinkGeneric
06/2012
1Biomarkers (Surrogate Marker)IBA
06/2012

Therapy/Procedure

2Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2018 - 04/2017
1Therapeutics
12/2018